What Is Semax?
Semax is a synthetic heptapeptide analog derived from the ACTH(4-10) fragment of adrenocorticotropic hormone. Originally developed in Russia, it is widely used in neuroscience research as a tool compound for studying cognition, neuroprotection, and neuroplasticity pathways. Greatest Peptides supplies Semax as a >99% pure lyophilized powder for laboratory research use only.
Semax 10 mg — Research Grade
Semax is a synthetic heptapeptide analog of an ACTH(4-10) fragment, widely studied in cognitive, neuroprotective, and neuroplasticity research models. Supplied as a lyophilized powder for controlled laboratory research only.
Specifications
- Compound: Semax (synthetic ACTH(4-10) heptapeptide analog)
- Quantity: 10 mg per vial, lyophilized powder
- Purity: 99%+ HPLC standard — batch-specific Certificate of Analysis included for your exact lot
- Identity: confirmed by LC-MS
- Appearance: white lyophilized powder
Documentation: Every vial ships with access to a batch-specific Certificate of Analysis showing HPLC purity, mass-spectrometry identity confirmation, endotoxin, residual solvents, and water content for your exact lot.
Handling & storage: Store lyophilized powder at -20°C. Reconstitute with bacteriostatic water for research handling. Keep out of direct light.
For laboratory and research use only. Not for human or animal consumption.
Semax Research Overview
In published preclinical literature, Semax has been investigated for its interaction with the brain-derived neurotrophic factor (BDNF) system and the melanocortin pathway. Research models have explored its relationship to BDNF and TrkB expression, dopaminergic and serotonergic signaling, and markers associated with neuroprotection following ischemic events. Because Semax is a short peptide that resists rapid enzymatic breakdown relative to native ACTH fragments, it is frequently used as a model compound in studies of nootropic and neurotrophic mechanisms.
These observations describe outcomes reported in laboratory and animal research models only. Semax is a research chemical — it is not a dietary supplement, drug, or therapeutic product, and nothing here describes effects in humans.
Related Research Topics
- Semax and BDNF expression in preclinical models
- Semax activity within the melanocortin system
- Semax vs. Selank in comparative behavioral research
Frequently Asked Questions
What is Semax used for in research?
Semax is used as a tool compound in cognitive, neuroprotective, and neuroplasticity research. It is studied for its interaction with BDNF and melanocortin signaling pathways in laboratory models.
Is Semax research use only?
Yes. All peptides from Greatest Peptides are supplied strictly for laboratory and research use only. They are not intended for human or veterinary use.
What purity is your Semax?
Our Semax is supplied at 99%+ HPLC purity, with a batch-specific Certificate of Analysis (COA) confirming purity by HPLC and identity by mass spectrometry for your exact lot.
How should Semax be stored?
Lyophilized Semax is typically kept refrigerated and protected from light for short-term research handling, and frozen (-20°C) for longer-term storage. Once reconstituted, it is generally kept refrigerated and used within the timeframe appropriate to the research protocol.
How is Semax supplied?
Semax ships as a white lyophilized (freeze-dried) powder, 10 mg per vial, requiring reconstitution with a suitable solvent such as bacteriostatic water prior to research use.





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