What Is KPV?
KPV is a synthetic tripeptide (lysine-proline-valine) corresponding to the C-terminal fragment of alpha-melanocyte-stimulating hormone (alpha-MSH). It is widely used as a research tool in inflammation and gut-barrier models. Greatest Peptides supplies KPV as a >99% pure lyophilized powder for laboratory research use only.
KPV, 10 mg per vial, a lysine-proline-valine tripeptide (lyophilized). For research use only.
Purity: ≥98% HPLC (see batch COA); identity confirmed by LC-MS. A batch-specific Certificate of Analysis (COA) is available for each lot. For laboratory and research use only. Not for human or animal consumption.
KPV Research Overview
In published preclinical literature, KPV has been investigated for its relationship to the NF-κB signaling pathway, modulation of pro-inflammatory cytokines, and intestinal epithelial transport via PepT1. It is frequently used as a model compound in colitis and mucosal-barrier research.
These observations describe outcomes reported in laboratory and animal research models only. KPV is a research chemical — it is not a dietary supplement, drug, or therapeutic product, and nothing here describes effects in humans.
Related Research Topics
- KPV and the NF-κB pathway
- Alpha-MSH fragment peptides in research
- KPV in gut-barrier models
Frequently Asked Questions
What is KPV used for in research?
KPV is used strictly as a tool compound in laboratory research, as described in the overview above. It is studied in controlled models only.
Is KPV research use only?
Yes. All compounds from Greatest Peptides are supplied strictly for laboratory and research use only. They are not intended for human or veterinary use.
What purity is your KPV?
Supplied at 99%+ HPLC purity with a batch-specific Certificate of Analysis (COA) confirming purity by HPLC and identity by mass spectrometry for your exact lot.
How should KPV be stored?
Lyophilized KPV is typically kept refrigerated and protected from light for short-term handling, and frozen (-20°C) for longer-term storage.
How is KPV supplied?
KPV ships as a white lyophilized powder, 10 mg per vial, requiring reconstitution with a suitable solvent prior to research use.

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